1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE

Biochemicals - Lipids

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Cat No: 21139

Biochemicals - Lipids

1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HETE (Item No. 34720) at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ion...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid, (1R)-2-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-1-[[(1-oxooctadecyl)oxy]methyl]ethyl ester

Correlated keywords:

3PE 15SHETE A-23187 15LO sn1 sn2 PEHETE 18:0p/15-HETE C18:0/15(S)-AA

Product Overview:
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. 10011298) at the sn-1 position and 15(S)-HETE (Item No. 34720) at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (Item No. 11016) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; Item No. 25871) by 15-LO.{42427,43514} Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes.

Size	50 µg
Shipping	dry ice
CAS Number	947381-58-0
Molecular Formula	C₄₃H₇₈NO₉P
SMILES	OP(OC[C@H](OC(CCC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)(OCCN)=O
Molecular Weight	784,1
Formulation	A solution in ethanol
Purity	≥98%
Custom Code	2916.19
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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