Prednisone

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Prednisone

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Cat No: 20677

Biochemicals - Lipids

Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressant activities.{19136} It inhibits paw swelling induced by sodium urate in mice by 86% when administered at a dose of 12 mg/kg.{42622} Prednisone reduces release of IL-6...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

17,21-dihydroxy-pregna-1,4-diene-3,11,20-trione

Correlated keywords:

68-59-7 synthetic corticosteroid immunosuppressant immunosuppression inflammatory CHOP combination therapy cyclophosphamide doxorubicin vincristine adasone ancortone apo-prednisone bicortone cartancyl colisone cordrol cortan cortidelt dacorten dacortin decortancyl decortin decortisyl dihydrocortisone dekortin delcortin dellacort dellacort-a delta-e delta-cortelan delta-dome deltacortene deltacortisone deltacortone deltasone deltison deltisona deltisone deltra di-adreson drazone econosone encorton encortone enkorton fernisone hostacortin liquid-pred me-korti metacortandracin meticorten NSC10023 nisona nurison orasone panafcort panasol paracort parmenison pehacort prednicen-m prednicorm prednicort prednicot prednidib prednidone prednilonga predniment prednisone prednitone pronison pulmison rectodelt retrocortine sone sterapred supercortil ultracorten ultracortene uniplen winpred ?-cortisone ?1-cortisone ?1-dehydrocortisone MCP3 IL6 MCP2 TNF? Rayos 1-Dehydrocortisone

Product Overview:
Prednisone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressant activities.{19136} It inhibits paw swelling induced by sodium urate in mice by 86% when administered at a dose of 12 mg/kg.{42622} Prednisone reduces release of IL-6, monocyte chemoattractant protein-2 (MCP-2), MCP-3, RANTES, and TNF-α in stented arteries in a rabbit model of atherosclerosis.{42623} Formulations containing prednisone have been used in the treatment of non-Hodgkin lymphoma as part of CHOP chemotherapy and as anti-inflammatory or immunosuppressive agents.

Size	1 g
Shipping	dry ice
CAS Number	53-03-2
Molecular Formula	C₂₁H₂₆O₅
SMILES	O=C(CO)[C@@]1(O)CC[C@@]([C@]1(C)C2)([H])[C@@]3([H])[C@]([C@](C=C4)(C)C(CC3)=CC4=O)([H])C2=O
Molecular Weight	358,4
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2932.99
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.