D-Glucose-6-phosphate (sodium sa

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D-Glucose-6-phosphate (sodium salt)

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Cat No: 20376

Biochemicals - More Biochemicals

D-Glucose-6-phosphate is formed in cells when glucose is phosphorylated by hexokinase (or glucokinase) or by the conversion of glucose-1-phosphate by phosphoglucomutase, which is the first step of glycogen synthesis.{20949} It is stored as glycogen wh...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

D-glucose-6-(dihydrogen phosphate), monosodium salt

Correlated keywords:

3671-99-6 56-73-5 3615-49-4 phosphorylated hexokinase glucokinase phosphoglucomutase glycogen synthesis hypoglycemia hepatomegaly glycolysis gluconeogenesis

Product Overview:
D-Glucose-6-phosphate is formed in cells when glucose is phosphorylated by hexokinase (or glucokinase) or by the conversion of glucose-1-phosphate by phosphoglucomutase, which is the first step of glycogen synthesis.{20949} It is stored as glycogen when blood glucose levels are high. Disruption of D-glucose-6-phosphate activity leads to glycogen storage disease type I or von Gierke’s disease, a group of inherited metabolic diseases characterized by severe hypoglycemia, growth retardation, and hepatomegaly, due to accumulation of glycogen and fat in the liver.{19698,19697} D-Glucose-6-phosphate is also the starting molecule of both glycolysis and the pentose phosphate pathways.{19695} Because cancer cells adopt glycolysis as a major source of metabolic energy production, and the pentose phosphate pathway plays a role in helping glycolytic cancer cells to meet their anabolic demands, this compound can be used to study the progression of this process.{26683}

Size	500 mg
Shipping	dry ice
CAS Number	54010-71-8
Molecular Formula	C₆H₁₂O₉P • Na
SMILES	O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)COP(O)([O-])=O.[Na+]
Molecular Weight	282,1
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2912.49
UNSPSC code	12352100

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MSDS

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