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4-Methylumbelliferyl-?-D-N,N',N''-Triacetylchitotrioside

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    4-<wbr/>Methyl<wbr/>umbelliferyl-<wbr/>?-<wbr/>D-<wbr/>N,N',N''-<wbr/>Triacetyl<wbr/>chitotrioside
  • 4-<wbr/>Methyl<wbr/>umbelliferyl-<wbr/>?-<wbr/>D-<wbr/>N,N',N''-<wbr/>Triacetyl<wbr/>chitotrioside
Cat No: 19715
Cayman

4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is a fluorogenic substrate for chitinases and chitotriosidases.{31643,31644,31645} 4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is cleaved by chitinases and chitotriosidases to relea...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 7-[[O-2-(acetylamino)-2-deoxy-?-D-glucopyranosyl-(1?4)-O-2-(acetylamino)-2-deoxy-?-D-glucopyranosyl-(1?4)-2-(acetylamino)-2-deoxy-?-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one
Correlated keywords:
  • 444311-04-0 697758-63-7 chitinase chitotriosidase fluorogenic MUFtriNAG MUFtri-NAG MUF-tri-NAG
Product Overview:
4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is a fluorogenic substrate for chitinases and chitotriosidases.{31643,31644,31645} 4-Methylumbelliferyl-β-D-N,N',N''-triacetylchitotrioside is cleaved by chitinases and chitotriosidases to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.{27251} It has been used to screen plasma samples for reduced chitotriosidase activity that may be indicative of lysosomal storage disorders.{31643}
Size 500 µg
Shipping dry ice
CAS Number 53643-13-3
Molecular Formula C34H47N3O18
SMILES CC(N[C@H]([C@H]1O)[C@H](OC2=CC=C(C(C)=CC(O3)=O)C3=C2)O[C@H](CO)[C@H]1O[C@@](O[C@@H]4CO)([H])[C@H](NC(C)=O)[C@@H](O)[C@@H]4O[C@]5([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5NC(C)=O)=O
Molecular Weight 785,8
Formulation A crystalline solid
Purity ≥98%
Custom Code 2922.19
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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