Triamcinolone acetonide

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Cat No: 18026

Biochemicals - Lipids

Triamcinolone acetonide is a synthetic corticosteroid.{43074} It decreases cytokine levels, the firing rate of sensory neurons, and mechanical hypersensitivity in a rat spinal nerve ligation model when used at a dose of 1.5 mg/kg prior to and followin...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

9-fluoro-11?,21-dihydroxy-16?,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione

Correlated keywords:

8054-16-8 13586-95-3 138265-06-2 911437-91-7 biochemical hormone receptor agonist arthritis immunology inflammation endocrinology allergy asthma steroid adcortyl aftach aristicort aristocort acetonide aristoderm azmacort berlicort delphicort extracort ftorocort I-vation ivation kenacort 40 kenacort 80 NSC21916 kenalog 10 ledercort cream lichtena maQuaid nasacort omcilon paralen pol'kortolon queyanshusong respicort rheudenolone rineton solodelf TAC-3 TAC-40 tamceton tramacin tri-Nasal triacet triakort triam 16,17-acetonide 16a,17a-acetonide triamcort-depot triamhexal triamonide trianopollon tricinolon triesence trivaris trymex valon vetalog vetazine volon volonimat

Product Overview:
Triamcinolone acetonide is a synthetic corticosteroid.{43074} It decreases cytokine levels, the firing rate of sensory neurons, and mechanical hypersensitivity in a rat spinal nerve ligation model when used at a dose of 1.5 mg/kg prior to and following surgery for three days. Triamcinolone acetonide also decreases outflow facility in a mouse model of steroid-induced glaucoma when 20 µl of a 40 mg/ml suspension is administered subconjunctivally.{43075} Formulations containing triamcinolone acetonide are used in the treatment of diabetic macular edema.

Size	100 mg
Shipping	dry ice
CAS Number	76-25-5
Molecular Formula	C₂₄H₃₁FO₆
SMILES	CC1(C)O[C@]2([H])C[C@@]3([H])[C@]4([H])CCC5=CC(C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(CO)=O)O1)=O
Molecular Weight	434,5
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2937.29
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.