Confirm delete?

Bertin Bioreagent
logo

Search

Contact Us
You are here :
  • Bioreagent   /
  • Product page
  • NMDA Receptor NR2A Subunit Polyclonal Antibody

NMDA Receptor NR2A Subunit Polyclonal Antibody

  • Photo non disponible
Cat No: 10608
Cayman
€683.00
Price is excluding VAT and does not include packaging neither shipping

Antigen: fusion protein from the C-terminus of the NR2A subunit of rat NMDA receptor • Host: rabbit • Cross Reactivity: (+) human, mouse, and rat NMDA receptor • Application(s): IHC, IP, and WB • The NMDAR plays an essential role in memory, neuronal ...

More
: 1 ea

This product can only be bought through Cayman Chemical. Please contact us.

- +
SHOOTING STAR BIOREAGENT - 20

Save 10% on every orders above 750 € (VAT Excl.)

 Save 20% on every orders above 1000 € (VAT Excl.)


SHOOTING STAR BIOREAGENT - 10

Save 10% on every orders above 750 € (VAT Excl.) 

Save 20% on every orders above 1000 € (VAT Excl.)


Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • CAY-10608
  • CAY-10608
Correlated keywords:
  • inhibits
  • inhibitors
  • neurotransmitters
  • WB
  • western
  • blots
  • blotting
  • receptors
Show more...
Product Overview:
Antigen: fusion protein from the C-terminus of the NR2A subunit of rat NMDA receptor • Host: rabbit • Cross Reactivity: (+) human, mouse, and rat NMDA receptor • Application(s): IHC, IP, and WB • The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. Channels with physiological activity are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.
The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-Daspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.
Size 1 ea
Shipping wet ice
Stability Store at -20 degrees; shelf life 365 days maximum after production
Host rabbit
Antigen fusion protein from the C-terminus of the NR2A subunit of rat NMDA receptor
Application(s)

IHC, IP, and WB

Specificity
Formulation 10 µg affinity-purified antibody lyophilized from 5 mM ammonium bicarbonate
Custom Code 3822000002
UNSPSC code 12352203

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : NMDA Receptor NR2A Subunit Polyclonal Antibody There are 10 products.