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15(R)-Prostaglandin F2?

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    15(R)-<wbr/>Prostaglandin F<sub>2?</sub>
  • 15(R)-<wbr/>Prostaglandin F<sub>2?</sub>
Cat No: 16740
Biochemicals - Lipids
Cayman

15(R)-PGF2α is the C-15 epimer of the naturally occurring mammalian autacoid PGF2α. It has only 25% of the potency of PGF2α in hamster antifertility studies,{1925} which may be due to reduced affinity for FP receptors. Compared to PGF2α, 15(R)-PGF2α h...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 9?,11?,15R-trihydroxy-prosta-5Z,13E-dien-1-oic acid
Correlated keywords:
  • 15(R)-PGF2.alpha. 15(R)-PGF2alpha 15R-PGF2alpha 15R-PGF2.alpha. prostaglandins 15(R)PGF2alpha 15(R)PGF2.alpha. 15-epi-PGF2alpha 15-epi-PGF2.alpha.
Product Overview:
15(R)-PGF2α is the C-15 epimer of the naturally occurring mammalian autacoid PGF2α. It has only 25% of the potency of PGF2α in hamster antifertility studies,{1925} which may be due to reduced affinity for FP receptors. Compared to PGF2α, 15(R)-PGF2α has a binding affinity of 6.7% to ovine luteal cell receptors.{2058} Similarly, the binding affinity to rat vascular smooth muscle cells is negligible as compared to PGF2α.{2057}
Size 500 µg
Shipping dry ice
CAS Number 37658-84-7
Molecular Formula C20H34O5
SMILES O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@H](O)CCCCC)[C@H](O)C1
Molecular Weight 354,5
Formulation A solution in methyl acetate
Purity ≥98%
Custom Code 2937.50
UNSPSC code 12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

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