2-Amino-5-fluorobenzoic Acid

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Cat No: 16669

Biochemicals - More Biochemicals

2-Amino-5-fluorobenzoic acid is a toxic antimetabolite for the tryptophan pathway in yeast that can be used to counterselect for TRP1, a commonly used genetic marker in S. cerevisiae.{27254} Because this trp1 strain lacks the enzymes required for the ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2-amino-5-fluoro-benzoic acid

Correlated keywords:

microbiology counterselection antimetabolite tryptophan pathway TRP1 genetic marker yeast S. cerevisiae Saccharomyces positive selection plasmid vector biochemical 675575-38-9 NSC513308 toxic anti-metabolite strain anthranilic acid feedback inhibition resistant 1891087-22-1

Product Overview:
2-Amino-5-fluorobenzoic acid is a toxic antimetabolite for the tryptophan pathway in yeast that can be used to counterselect for TRP1, a commonly used genetic marker in S. cerevisiae.{27254} Because this trp1 strain lacks the enzymes required for the conversion of anthranilic acid to tryptophan, it is resistant to 2-amino-5-fluorobenzoic acid feedback inhibition, enabling a growth-based, positive selection of the TRP1 marker. 2-Amino-5-fluorobenzoic acid is frequently used in genetic procedures that involve plasmid manipulations.{27254}

Size	1 g
Shipping	dry ice
CAS Number	446-08-2
Molecular Formula	C₇H₆FNO₂
SMILES	NC1=C(C(O)=O)C=C(F)C=C1
Molecular Weight	155,1
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2908.99
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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