Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

DL-Sulforaphane N-acetyl-L-cysteine

  • Zoom
    DL-<wbr/>Sulforaphane N-acetyl-L-<wbr/>cysteine
  • DL-<wbr/>Sulforaphane N-acetyl-L-<wbr/>cysteine
Cat No: 16098
Biochemicals - Small Molecule Inhibitors
Cayman

Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress.{17702} Unless activated by inflammatory, environmental, or oxidative stressors, Nrf2 is sequestered in...

More

This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • N-acetyl-S-[[[4-(methylsulfinyl)butyl]amino]thioxomethyl]-L-cysteine
Correlated keywords:
  • Nrf2 antioxidant anti-oxidant anti oxidant cancers anti-cancers sulforaphane anticancer Keap1 ARE iosthiocyanate acetyl cysteine metabolite sulforaphane chemopreventative enzymes Nrf2 genes expression HepG2-C8 cells agents SFN NAC SFNNAC SFN NAC transcriptions factors oxidative injury injuries intracellular signaling responses elements signals inflammation
Product Overview:
Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress.{17702} Unless activated by inflammatory, environmental, or oxidative stressors, Nrf2 is sequestered in the cytoplasm by its repressor, Keap1.{16386} Because of its protective capabilities, small molecules that activate Nrf2 signaling are being examined as potential anti-cancer or anti-inflammatory agents.{20661} DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC) is a major metabolite of SFN (Item No. 10496), a powerful inducer of chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression.{21473,26231} At 75 µM, SFN-NAC has been shown to increase ARE expression in HepG2-C8 cells.{26230} Its reported potency on ARE-related gene expression is roughly 8-fold less than SFN.{26230}
Size 1 mg
Shipping dry ice
CAS Number 334829-66-2
Molecular Formula C11H20N2O4S3
SMILES OC([C@@H](NC(C)=O)CSC(NCCCCS(C)=O)=S)=O
Molecular Weight 340,5
Formulation A crystalline solid
Purity ≥98%
Custom Code 2930.90
UNSPSC code 12352100

Click here to ask for your quote and get 15% off Cayman's products.

 

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : DL-<wbr/>Sulforaphane N-acetyl-L-<wbr/>cysteine There are 2 products.

Search