(R)-Prunasin

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(R)-Prunasin

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Cat No: 15959

Biochemicals - Small Molecule Inhibitors

(R)-Prunasin is a cyanogenic glucoside that is the precursor to amygdalin, a bitter component found in species of the genera Prunus and Olinia.{25883} It can be degraded to hydrogen cyanide, glucose, and benzaldehyde by the action of prunasin hydrolas...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

?R-(?-D-glucopyranosyloxy)-benzeneacetonitrile

Correlated keywords:

1300-?20-?5 natural products plants growths glucosides amygdalin cyanides DNAs polymerases ? inhibitors bases excision repairs damages beta .beta. b cyanogenic precursors hydrogens degraded degradation glucoses benzaldehyde (R) Rs D-Prunasin Ds 2R bitter Prunus Olinia hydrolase mandelonitrile lyases inhibitory effects inhibits inhibitors inhibitions rats maintenances replications

Product Overview:
(R)-Prunasin is a cyanogenic glucoside that is the precursor to amygdalin, a bitter component found in species of the genera Prunus and Olinia.{25883} It can be degraded to hydrogen cyanide, glucose, and benzaldehyde by the action of prunasin hydrolase and mandelonitrile lyase and possesses inhibitory effects on plant growth.{25883} (R)-Prunasin reportedly inhibits rat DNA polymerase β, which performs base excision repair required for DNA maintenance and replication, with an IC50 value of 98 µM.{25882}

Size	500 µg
Shipping	dry ice
CAS Number	99-18-3
Molecular Formula	C₁₄H₁₇NO₆
SMILES	O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O[C@@H](C#N)C2=CC=CC=C2)[C@@H]1O
Molecular Weight	295,3
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2837.19
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.