Ramipril

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Ramipril

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Cat No: 15558

Biochemicals - Small Molecule Inhibitors

Ramipril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor ramiprilat (Item No. 15557).{23056} Ramipril (2.5 mg/kg per day, p.o.) reduces systolic blood pressure in spontaneously hypertensive rats.{36825} It reduces aortic valve b...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-cyclopenta[b]pyrrole-2-carboxylic acid

Correlated keywords:

126613-?39-?6 antihypertension hypertension heart failure diabetes ACE inhibitors inhibitions inhibits converting angiotensin angiotensin-converting enzyme angiotensin I angiotensin II vasoconstriction renin-angiotensin system prodrug ramiprilat renin systems prodrugs cardiology diabetes vascular diseases altace cardace corpril delix ecator HOE 498 HOE498 HOE-498 hopace pramace ramace ramipres rampicardin triatec tritace unipril vesdil

Product Overview:
Ramipril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor ramiprilat (Item No. 15557).{23056} Ramipril (2.5 mg/kg per day, p.o.) reduces systolic blood pressure in spontaneously hypertensive rats.{36825} It reduces aortic valve backscatter and improves aortic flow in a rabbit model of aortic valve stenosis.{36826} Ramipril also decreases paw swelling and serum levels of TNF-α and prostaglandin E2 (PGE2) as well as cardiac collagen deposition and fibrosis in a rat model of adjuvant-induced arthritis.{36827}

Size	100 mg
Shipping	dry ice
CAS Number	87333-19-5
Molecular Formula	C₂₃H₃₂N₂O₅
SMILES	O=C([C@H](C)N[C@H](C(OCC)=O)CCC1=CC=CC=C1)N2[C@]3([H])[C@](CCC3)([H])C[C@H]2C(O)=O
Molecular Weight	416,5
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2922.19
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.