Minoxidil

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Minoxidil

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Cat No: 15302

Biochemicals - Ion Channel Modulation

Minoxidil is a pyrimidine derivative that was originally developed as an anti-hypertensive agent and unexpectedly found to stimulate hair growth. Minoxidil directly affects arteriolar smooth muscle to decrease vascular resistance in part by opening AT...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

6-(1-piperidinyl)-2,4-pyrimidinediamine 3-oxide

Correlated keywords:

16317-69-4 hairs growths vasodilators antihypertensive anti hypertensive anti-hypertensive COX-1 COXs 1 cyclooxygenases one COX1 activators activates KATP channels ATP-sensitive potassium ATPs prostaglandins E2 PGs PGE2 alopexil alostil loniten lonolox minoximen mintop normoxidil PDP pierminox prexidil riUP rogaine tricoxidil Us 10858 U-10858 U10858 pyrimidine derivatives arteriolar smooth muscles vascular resistance

Product Overview:
Minoxidil is a pyrimidine derivative that was originally developed as an anti-hypertensive agent and unexpectedly found to stimulate hair growth. Minoxidil directly affects arteriolar smooth muscle to decrease vascular resistance in part by opening ATP-sensitive potassium channels.{24983,24984} It can activate cyclooxygenase 1 (AC50 = 80 μM), which is expressed in the dermal papilla of hair follicles, increasing prostaglandin E2 production in BALB/c 3T3 fibroblasts and human dermal papilla fibroblasts.{4171}

Size	100 mg
Shipping	dry ice
CAS Number	38304-91-5
Molecular Formula	C₉H₁₅N₅O
SMILES	NC1=[N+]([O-])C(N)=NC(N2CCCCC2)=C1
Molecular Weight	209,3
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2933.59
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.