1,2-Dioleoyl-sn-glycero-3-PE

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Cat No: 15091

Biochemicals - Lipids

1,2-Dioleoyl-sn-glycero-3-PE (1,2-DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. The compound features the same diacylglycerol stereochemistry as that of the natural compound. 1,2-DOPE...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine

Correlated keywords:

143062-82-2 DOPEs phosphoethanolamine phospho ethanolamines phosopholipids lipids liposome DNA transfection genes therapy therapies emulsifier cationic phospholipids dioleoyl sn glycerol natural naturally occurring occurs C18:1 fatty acids sns sn-1 sn1 sn-2 sn2 one two 1 2 diacylglycerol stereochemistry emulsifier DNA-liposomes membranes cationic non-viral nonviral non virals coatsome ME MC ME8181 ME-8181 8181 MC-8181 MC8181 8181

Product Overview:
1,2-Dioleoyl-sn-glycero-3-PE (1,2-DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. The compound features the same diacylglycerol stereochemistry as that of the natural compound. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.{9185,24259,24260}

Size	100 mg
Shipping	dry ice
CAS Number	01/05/4004 00:00
Molecular Formula	C₄₁H₇₈NO₈P
SMILES	CCCCCCCC/C=C\CCCCCCCC(O[C@@H](COP(OCC[NH3+])([O-])=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O
Molecular Weight	744,1
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2932.99
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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