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Methylprednisolone

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    Methyl<wbr/>prednisolone
  • Methyl<wbr/>prednisolone
Cat No: 15013
Biochemicals - Lipids
Cayman

Prednisolone is the active metabolite of the synthetic corticosteroid prednisone, which is used to suppress inflammation and autoimmunity, as well as in other conditions.{19136} Methylprednisolone is a 6α-methyl derivative of prednisolone, a variation ...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 11?,17,21-trihydroxy-6?-methyl-pregna-1,4-diene-3,20-dione
Correlated keywords:
  • 570-35-4 121673-01-6 hormones receptors agonists inflammations autoimmune diseases arthritis endocrinology immunology prednisolone methyl-prednisolone methyls metabolites 6? -methyl 6alpha 6.alpha. 6a bindings binds corticosteroids globulins penetrations tissues genes expressions glucocorticoids mineralocorticoids A-Methapred A methapred besonia dopomedrol dopo Medrol dopo-medrol duralone M-prednisol M prednisol medorol medralone medrate medrone metastab methylprednisolone methypred metilbetasone metilprednisolone metipred metrisone modern NSCs 19987 NSC-19987 NSC19987 prednol L prednol-L promacortine solimedrol suprametil U-7532 U7532 U 7532 wyacort urbason urbasone urbazone synthetics autoimmunity derivatives corticosteroid-binding targets
Product Overview:
Prednisolone is the active metabolite of the synthetic corticosteroid prednisone, which is used to suppress inflammation and autoimmunity, as well as in other conditions.{19136} Methylprednisolone is a 6α-methyl derivative of prednisolone, a variation which reduces its binding to corticosteroid-binding globulin and increases penetration into target tissues.{19136} It alters gene expression, like prednisolone, through both the glucocorticoid and mineralocorticoid receptors.{22687}
Size 500 mg
Shipping dry ice
CAS Number 83-43-2
Molecular Formula C22H30O5
SMILES O=C1C=C[C@@]2(C)C([C@@H](C)C[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1
Molecular Weight 374,5
Formulation A crystalline solid
Purity ≥98%
Custom Code 2932.99
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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