Tetracycline (hydrochloride)

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Cat No: 14328

Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site.{22680} It is...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(4S,4aS,5aS,6S,12aS)- 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide, monohydrochloride

Correlated keywords:

60-54-8 8017-77-4 8026-72-0 90438-83-8 102030-19-3 molecular broad spectrum broad-spectrum inhibitors inhibits inhibitions antibiotics proteins synthesis 30S ribosomes ribosomal cells biology cultures subunits tetR genes bacterial resistance prevents aminoacyl attachments growth selective agents toxic prokaryotic toxicity prokaryotics prokaryotes eukaryotes eukaryotics tRNA transfer RNA ribonucleic acids acceptor sites eukaryotic HCl achro achromycin ala-tet alatet ala tet ambracyn bristaciclina bristacycline cancycline-250 250 cancycline cefracycline criseociclina cyclopar diocyclin dumocyclin helvcyclin hostacyclin hostacyckube imex laudin medamycin neocycline b neocycline-b paltet panmycin partrex polycycline polyotic ointment purocyclina quadracyclin remicyclin riocyclin ro-cycline ro cycline robitet sanclomycine steclin subamycin sustamycin talcin tefilin tet-cy tet cy tetcy tetrasure tetra sure tetra-sure tetrabakat tetrabid tetrablet tetrabon tetracaps tetrachel tetracompren tetracycline chlorohydrate tetracyklin tetracyn tetrakap tetralution tetramavan tetrosol topicycline totomycin triphacyclin unicin vetquamycin 324

Product Overview:
Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site.{22680} It is used in cell biology as a selective agent in cell culture systems. Tetracycline is toxic to prokaryotic and eukaryotic cells and selects for cells harboring the bacterial tetR gene, which are resistant to the antibiotic.{17511}

Size	10 g
Shipping	dry ice
CAS Number	64-75-5
Molecular Formula	C₂₂H₂₄N₂O₈ • HCl
SMILES	O=C1C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@](C3=C(O)[C@@]21O)([H])[C@@](O)(C)C4=CC=CC(O)=C4C3=O.Cl
Molecular Weight	480,9
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2922.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.