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Gatifloxacin

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    Gatifloxacin
  • Gatifloxacin
Cat No: 14290
Cayman

Gatifloxacin is a fluoroquinolone antibiotic which inhibits bacterial DNA gyrase (IC50 = 0.109 μg/ml) and topoisomerase IV (IC50 = 13.8 μg/ml).{22453} It is much less effective against HeLa cell topoisomerase II (IC50 = 265 μg/ml).{22453} Gatifloxin h...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Correlated keywords:
  • 160738-57-8 antibiotics inhibitors inhibits inhibitions fluoroquinolones bacterial DNA deoxyribonucleic acids gyrases enzymes topoismerases IV 4 HeLa cells II 2 broad spectrums broad-spectrum oral producing produces dysglycemia conjunctivitis topoisomerase-IV AM-1155 AM1155 AMs 1155 BMS 206584-01 20658401 206584 01 BMS-206584-01 BMS-206584 BMS-20658401 BMS206584-01 BMS206584 BMS20658401 G-Cebran G cebran gaity gatiflo gatilox gatiquin gatispan PD135432 PDs 135432 PD-135432 tequin tymer zymar gatifloxin
Product Overview:
Gatifloxacin is a fluoroquinolone antibiotic which inhibits bacterial DNA gyrase (IC50 = 0.109 μg/ml) and topoisomerase IV (IC50 = 13.8 μg/ml).{22453} It is much less effective against HeLa cell topoisomerase II (IC50 = 265 μg/ml).{22453} Gatifloxin has been used as a broad-spectrum oral antibiotic, but it can produce dysglycemia in older adults.{22452} It remains useful for resolving bacterial conjunctivitis.{22451}
Size 1 g
Shipping dry ice
CAS Number 112811-59-3
Molecular Formula C19H22FN3O4
SMILES CC1NCCN(C2=C(OC)C(N(C3CC3)C=C(C(O)=O)C4=O)=C4C=C2F)C1
Molecular Weight 375,4
Formulation A crystalline solid
Purity ≥98%
Custom Code 2903.99
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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