Oxyresveratrol

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Oxyresveratrol

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Cat No: 12028

Biochemicals - Lipids

Resveratrol is a potent phenolic antioxidant found in the skin of grapes and red wine that has anti-proliferative, anti-inflammatory, and cardioprotective properties.{9146} Oxyresveratrol is a naturally occurring analog of resveratrol found in mulberry...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-1,3-benzenediol

Correlated keywords:

33626-05-0 resveratrol antioxidant free radical scavenger neuroprotection strokes ischemia tyrosinase melanin depigmentation skin whitening natural analogs mulberry woods H2O2 NO DPPH 2,2-diphenyl-I-picrylhydrazyl cytochromes c caspase 3 caspase-s inhibits inhibiting inhibitors inhibitions pigments kojic acids hyperpigmentation disorders B16 B 16 B-16

Product Overview:
Resveratrol is a potent phenolic antioxidant found in the skin of grapes and red wine that has anti-proliferative, anti-inflammatory, and cardioprotective properties.{9146} Oxyresveratrol is a naturally occurring analog of resveratrol found in mulberry wood. It effectively scavenges H2O2, NO (IC50 = 45.3 μM), and the artificial free radical 2,2-diphenyl-l-picrylhydrazyl (IC50 = 28.9 μM).{21433} At 10 mg/kg, oxyresveratrol acts as a neuroprotectant, reducing brain infarct volume and reducing cytochrome c release and caspase-3 activation in an in vivo model of stroke.{12512} Oxyresveratrol also has depigmenting effects by effectively inhibiting tyrosinase activity, which catalyzes the rate-limiting step in synthesizing melanin pigments (IC50s = 1.2 and 52.7 μM in mushroom and mouse melanoma B-16 cells, respectively).{21434} It is 32-fold more potent than kojic acid, a depigmenting agent used in cosmetic materials with skin-whitening effects and medical agents used to treat hyperpigmentation disorders.{21434}

Size	50 mg
Shipping	dry ice
CAS Number	29700-22-9
Molecular Formula	C₁₄H₁₂O₄
SMILES	OC1=CC(O)=CC(/C=C/C2=C(O)C=C(O)C=C2)=C1
Molecular Weight	244,2
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2907.29
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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