Prostaglandin D2-1-glyceryl este

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Prostaglandin D₂-1-glyceryl ester

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Cat No: 12015

Biochemicals - Lipids

2-Arachidonoyl glycerol (2-AG; Item No. 62160) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.{4614,5306} Incubation of 2-AG with COX-2 and specific prostaglandin H2 (PGH2; I...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

9?,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid, 1-glyceryl ester

Correlated keywords:

endocannabinoids anandamides 2AG fatty acids porcine brain isomerase moiety cannabinoids cbs synthetic

Product Overview:
2-Arachidonoyl glycerol (2-AG; Item No. 62160) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.{4614,5306} Incubation of 2-AG with COX-2 and specific prostaglandin H2 (PGH2; Item No. 17020) isomerases in cell cultures and isolated enzyme preparations results in prostaglandin glycerol ester formation.{11045} The biosynthesis of PGH, PGD, PGE, PGF, and TXA-2-glyceryl ester compounds have all been documented. In RAW 264.7 cells, PGD2-2-glyceryl ester is the main COX metabolite.{11045} The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 mixture of the 1- and 2-glyceryl esters in typical aqueous media. While the stability and metabolism of these PG products have been investigated, little is known about their intrinsic biological activity.{10555}

Size	1 mg
Shipping	dry ice
CAS Number	309260-52-4
Molecular Formula	C₂₃H₃₈O₇
SMILES	CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1C/C=C\CCCC(=O)OCC(O)CO
Molecular Weight	426,6
Formulation	A solution in acetonitrile
Purity	≥95% (as a 9:1 mixture of the 1- and 2-glyceryl esters)
Custom Code	2937.50
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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Prostaglandin D2-1-glyceryl ester