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Bacoside A3

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    Bacoside A<sub>3</sub>
  • Bacoside A<sub>3</sub>
Cat No: 11824
Biochemicals - Natural Products
Cayman

Bacoside A3 is a triterpenoid saponin first isolated from B. monniera.{39061} Bacoside A3 inhibits the ATP-binding cassette transporter P-glycoprotein (P-gp), decreasing efflux 4-fold compared with control in vitro.{39064} An extract containing bacosi...

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: 5 mg

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • (3?,16?,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-?-L-arabinofuranosyl-(1?2)-O-[?-D-glucopyranosyl-(1?3)]-?-D-glucopyranoside
Product Overview:
Bacoside A3 is a triterpenoid saponin first isolated from B. monniera.{39061} Bacoside A3 inhibits the ATP-binding cassette transporter P-glycoprotein (P-gp), decreasing efflux 4-fold compared with control in vitro.{39064} An extract containing bacoside A3 and bacopaside II (4 and 1.3 µg/mg extract, respectively) administered for eight days at a dose of 10-30 mg/kg reduces opioid withdrawal-induced depression in mice using the forced swim test.{39062} Bacoside A3 also has antioxidant properties following liver and kidney damage induced by street heroin in rats.{39063}
Size 5 mg
Shipping dry ice
CAS Number 157408-08-7
Molecular Formula C47H76O18
SMILES CC1(O)CC(/C=C(C)/C)OC2(OC3)CC43C5(C)CCC6C(C)(C)C(OC7OC(CO)C(O)C(OC8OC(CO)C(O)C(O)C8O)C7OC9OC(CO)C(O)C9O)CCC6(C)C5CCC4C21
Molecular Weight 929,1
Formulation A solid
Purity ≥98%
Custom Code 2932.99
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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