Vincamine

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Vincamine

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Cat No: 11763

Biochemicals - Natural Products

Vincamine is an indole alkaloid found in the leaves of V. minor and C. roseus that is used as a peripheral vasodilator to increase blood flow to the brain.{21128} Vincamine contracts excised human cerebrovascular smooth muscle in vitro with an EC50 va...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(3?,14?,16?)-14,15-dihydro-14-hydroxy-eburnamenine-14-carboxylic acid, methyl ester

Correlated keywords:

10597-62-3 devinkan methyl vincaminate NSC-91998 NSC91998 ocu-vinc oxygeron pervincamine pervone arteriovinca vincadar vincafarm vincafolina vincafor vincagil vincalen vincamidol vincamin vincapan vincapront vincimax vinodrel retard vinvasaunier vraap cis-vincamine alkaloids catharanthus roseus vinca minor vasodilation cerebral blood flow vascular diseases C. roseus v. minor leaves increases brains in vitro pharmacotherapy

Product Overview:
Vincamine is an indole alkaloid found in the leaves of V. minor and C. roseus that is used as a peripheral vasodilator to increase blood flow to the brain.{21128} Vincamine contracts excised human cerebrovascular smooth muscle in vitro with an EC50 value of 30 μM and has been explored as a pharmacotherapy to treat cerebral metabolic and vascular diseases.{21127,21129}

Size	500 mg
Shipping	dry ice
CAS Number	1617-90-9
Molecular Formula	C₂₁H₂₆N₂O₃
SMILES	CC[C@]1(CCC2)C[C@@](C(OC)=O)(O)N3C4=CC=CC=C4C5=C3[C@@]1([H])N2CC5
Molecular Weight	354,4
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2933.49
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.