Confirm delete?

Bertin Bioreagent
logo
All categories
Contact Us
You are here :

Tetrahydropiperine

  • Zoom
    Tetrahydro<wbr/>piperine
  • Tetrahydro<wbr/>piperine
Cat No: 11758
Biochemicals - Small Molecule Inhibitors
Cayman

Tetrahydropiperine is a derivative of piperine (Item No. 11750) and an arylpentanamide originally isolated from P. longum that has diverse biological activities.{47189,47190} It is an agonist of transient receptor potential vanilloid type 1 (TRPV1; EC...

More

This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-1-pentanone
Correlated keywords:
  • Piper TRP V1TRPV P 450 1A1 Cosmoperine Tetrahydropiperidine
Product Overview:
Tetrahydropiperine is a derivative of piperine (Item No. 11750) and an arylpentanamide originally isolated from P. longum that has diverse biological activities.{47189,47190} It is an agonist of transient receptor potential vanilloid type 1 (TRPV1; EC50 = 6.3 µM).{47190} It inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH; IC50 = 23 µM) and 7-methoxycoumarin O-demethylase (MOCD) activity (IC50 = 25 µM) in rat liver microsomes.{47191} Tetrahydropiperine increases skin pigmentation in a mouse model of vitiligo when 100 µl of a 175 mM solution is administered topically, an effect that can be enhanced by subsequent suberythemal ultraviolet radiation (UVR).{47192} Formulations containing tetrahydropiperine have been used to increase bioavailability of compounds applied to the skin.
Size 1 mg
Shipping dry ice
CAS Number 23434-88-0
Molecular Formula C17H23NO3
SMILES O=C(CCCCC1=CC(OCO2)=C2C=C1)N3CCCCC3
Molecular Weight 289,4
Formulation A solution in ethanol
Purity ≥95%
Custom Code 2933.39
UNSPSC code 12352100

Click here to ask for your quote and get 15% off Cayman's products.

 

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : Tetrahydro<wbr/>piperine There is one product.

Search