Ochratoxin A

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Ochratoxin A

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Cat No: 11439

Biochemicals - Toxins

Ochratoxin A (OTA) is a mycotoxin that has been found in Aspergillus and Penicillium.{21687} It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a do...

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Territorial Availability: Available through Bertin Technologies only in France

                                            Technical Warning: Bertin Technologies restricts the sale of this product to licensed controlled substance laboratories and qualified academic research institutions. Please contact us for further details.
                    

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Synonyms:

N-[[(3R)-5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine

Correlated keywords:

19850-84-1 26153-09-3 3R,14S-ochratoxin A NSC201422 NSC-201422 NSC221991 NSC-221991 phenylalanine-ochratoxin A mycotoxins Aspergillus ochraceus carbonarius Penicillium verrucosum food contaminants nephropathy renal skin cancers oxidative stress Nrf2 MAPK DNA damage ochratoxin-A A. ochraceus A. carbonarius P. verrucosum neurons immune systems liver kidneys organs adenomas tumors tolerable weekly intake Phe-OTA

Product Overview:
Ochratoxin A (OTA) is a mycotoxin that has been found in Aspergillus and Penicillium.{21687} It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.{57301} Topical application of ochratoxin A (80 μg/mouse) induces DNA damage, cell cycle arrest at the G0/G1 phase, and apoptosis in mouse skin cells.{21687} It also initiates tumor formation in a two-stage mouse skin tumorigenesis model. Ochratoxin A has been found as a contaminant in a variety of foods.{21686}

Size	1 mg
Shipping	dry ice
CAS Number	303-47-9
Molecular Formula	C₂₀H₁₈ClNO₆
SMILES	O=C(O)C(NC(C1=CC(Cl)=C(C[C@@H](C)OC2=O)C2=C1O)=O)CC3=CC=CC=C3
Molecular Weight	403,8
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2908.99
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.