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4-deoxy Nivalenol

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    4-deoxy Nivalenol
  • 4-deoxy Nivalenol
Cat No: 11428
Biochemicals - Toxins
Cayman

4-deoxy Nivalenol is a trichothecene mycotoxin that has been found in Fusarium.{24416} It binds to eukaryotic ribosomes and inhibits protein synthesis in mice when administered at doses ranging from 5 to 25 mg/kg. 4-deoxy Nivalenol (0.1 and 0.2 mg/kg)...

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Territorial Availability: Available through Bertin Technologies only in France
Technical Warning: Bertin Technologies restricts the sale of this product to licensed controlled substance laboratories and qualified academic research institutions. Please contact us for further details.
Special Advice: Please check regulation status before ordering; additionel fees can apply.
Synonyms:
  • 12,13-epoxy-3?,7?,15-trihydroxy-trichothec-9-en-8-one
Correlated keywords:
  • mycotoxins toxicology nutrition natural products type B type-B trichothecene fungus fungi fusarium cereal crops wheat barley oats maize rye induces vomiting vomits diarrhea weight loss immunotoxicity anorexia NSCs 269144 NSC-269144 NSC269144 4-deoxynivalenol 4-desoxynivalenol dehdronivalenol peptidyl transferase deoxynivalenol
Product Overview:
4-deoxy Nivalenol is a trichothecene mycotoxin that has been found in Fusarium.{24416} It binds to eukaryotic ribosomes and inhibits protein synthesis in mice when administered at doses ranging from 5 to 25 mg/kg. 4-deoxy Nivalenol (0.1 and 0.2 mg/kg) induces emesis in pigs and decreases feed consumption in pigs when administered at a dose of 40 ppb in the diet.{58158} It induces lethality in mice (LD50 = 46-78 mg/kg).{58159} 4-deoxy Nivalenol has been found in F. graminearum-infected cereal grains such as wheat, barley, and corn.
Size 500 µg
Shipping dry ice
CAS Number 51481-10-8
Molecular Formula C15H20O6
SMILES CC1=C[C@]2([H])[C@]([C@](C[C@H]3O)(C)[C@]4(CO4)[C@]3([H])O2)(CO)[C@H](O)C1=O
Molecular Weight 296,3
Formulation A crystalline solid
Purity ≥98%
Custom Code 2932.99
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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