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diacetoxy Scirpenol

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    diacetoxy Scirpenol
  • diacetoxy Scirpenol
Cat No: 11427
Biochemicals - Toxins
Cayman
€73.00
Price is excluding VAT and does not include packaging neither shipping

diacetoxy Scirpenol (DAS) is a potent, trichothecene mycotoxin produced by certain Fusarium strains, which play an important role as plant pathogens, causing a wide range of diseases.{20564} It is toxic to fungi, plants, animals, and various mammalian...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Pharma only in Europe
Special Advice: LETTER OF ASSURANCE NEEDED - special handling and administrative fees : 150€
Synonyms:
  • (3α,4β)-12,13-epoxy-4,15-diacetate-trichothec-9-ene-3,4,15-triol
Correlated keywords:
  • 11011-10-2 22135-66-6 25662-95-7 28776-47-8 109547-11-7 145427-91-4 852223-87-1 scirpenetriol trichothecene mycotoxins Fusarium toxins inhibitors inhibits inhibition proteins synthesis plants defense immune response pathogens diseases Arabidopsis MAMP genes cells NSC141537 NSC-141537 NSC177378 NSC-177378
Product Overview:
diacetoxy Scirpenol (DAS) is a potent, trichothecene mycotoxin produced by certain Fusarium strains, which play an important role as plant pathogens, causing a wide range of diseases.{20564} It is toxic to fungi, plants, animals, and various mammalian cell cultures, inhibiting de novo protein synthesis.{20563} In a biological activity assay, DAS was shown to inhibit expression of the Arabidopsis MAMP-responsive reporter gene WRKY29p::GUS with an IC50 value of 50 nM, thereby suppressing a rapid cell death immune response important for plant defense.{20565}
Size 1 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 2270-40-8
Molecular Formula C19H26O7
SMILES CC1=C[C@]2([H])[C@]([C@]([C@H](OC(C)=O)[C@H]3O)(C)[C@@]4(OC4)[C@]3([H])O2)(COC(C)=O)CC1
Molecular Weight 366,4
Formulation A crystalline solid
Purity ≥98%
Custom Code 2910.90
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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