Clofibrate

Confirm delete?

Clofibrate

Zoom

Cat No: 10956

Biochemicals - Receptor Pharmacology

Clofibrate is a selective agonist of peroxisome proliferator-activated receptor α (PPARα).{10670} In a transactivation assay, clofibrate exhibits EC50 values of 50 and 55 µM for murine and human PPARα, respectively. It also binds to PPARγ but with 10-...

This product can only be bought through Cayman Chemical. Please contact us.

Product Overview
Data
Downloads
About Cayman

Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2-(4-chlorophenoxy)-2-methyl-propanoic acid, ethyl ester

Correlated keywords:

AY 61123 AY61123 Abitrate Amotril Anparton Apolan Arteriosan Artevil Ateculon Ateriosan Atheropront Atromid S Atromidin Azionyl Bioscleran CPIB Cartagyl Claripex Clobren SF Clofibrat Clofinit ECPIB EPIB Hyclorate ICI28257 Lipavil Lipavlon Lipomid Liprinal Miscleron Misclerone NSC79389 Neo-Atromid Normet Normolipol Recolip Regelan Serotinex Sklerepmexe Sklero-Tablinene Sklerolip Skleromexe Ticlobran Xyduril Chlorophenoxyisobutyric PPAR-? ? ? PPARa PPARd PPARg

Product Overview:
Clofibrate is a selective agonist of peroxisome proliferator-activated receptor α (PPARα).{10670} In a transactivation assay, clofibrate exhibits EC50 values of 50 and 55 µM for murine and human PPARα, respectively. It also binds to PPARγ but with 10-fold less affinity and is inactive at PPARδ at concentrations up to 100 µM. Formulations containing clofibrate have been used to treat dyslipidemia and cardiovascular disease.

Size	500 mg
Shipping	dry ice
CAS Number	637-07-0
Molecular Formula	C₁₂H₁₅ClO₃
SMILES	ClC1=CC=C(OC(C)(C)C(OCC)=O)C=C1
Molecular Weight	242,7
Formulation	A neat oil
Purity	≥98%
Custom Code	2903.99
UNSPSC code	12352100

Technical File

MSDS

Click here to ask for your quote and get 15% off Cayman's products.

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.