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(±)-JWH 018 N-(4-hydroxypentyl) metabolite-d5

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    (±)-<wbr/>JWH 018 N-<wbr/>(4-<wbr/>hydroxypentyl) metabolite-<wbr/>d<sub>5</sub>
  • (±)-<wbr/>JWH 018 N-<wbr/>(4-<wbr/>hydroxypentyl) metabolite-<wbr/>d<sub>5</sub>
Cat No: 10926
Biochemicals - Isotopically Labeled Standards
Cayman
€125.00
Price is excluding VAT and does not include packaging neither shipping

(±)-JWH 018 N-(4-hydroxypentyl) metabolite-d5 contains five deuterium atoms at the 2, 5, 6, 7, and 8 positions. It is intended for use as an internal standard for the quantification of (±)-JWH 018 N-(4-hydroxypentyl) metabolite by GC- or LC-mass spect...

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Territorial Availability: Available through Bertin Pharma only in Europe
Synonyms:
  • (1-(4-hydroxypentyl)-2,5,6,7,8-d5-1H-indol-3-yl)(naphthalen-1-yl)-methanone
Correlated keywords:
  • JWH-018 JWH018 JWH18 JWH-18 JWH18 cannabinoids WIN 55,212-2 urinary metabolites forensics CBs WIN 55212-2 WIN 55,212-2 WIN55,212-2 WIN55212-2 monohydroxylation metabolism N-alkyl chains agonists peripheral central receptors smoking mixtures GC/MS deuteriums standards deuterateds LC/MS GC-MS LC-MS mass spectrometry analytical references standards
Product Overview:
(±)-JWH 018 N-(4-hydroxypentyl) metabolite-d5 contains five deuterium atoms at the 2, 5, 6, 7, and 8 positions. It is intended for use as an internal standard for the quantification of (±)-JWH 018 N-(4-hydroxypentyl) metabolite by GC- or LC-mass spectrometry. JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06.{16797} JWH 018 is one of several synthetic CBs which have been included in smoking mixtures.{18291,19507} (±)-JWH 018 N-(4-hydroxypentyl) metabolite is a urinary metabolite of JWH 018, characterized by monohydroxylation of the N-alkyl chain.{19353} Its biological actions are unknown.
Size 100 µg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 1413427-49-2
Molecular Formula C24H18D5NO2
SMILES O=C(C1=CC=CC2=C1C=CC=C2)C3=C([2H])N(CCCC(O)C)C4=C([2H])C([2H])=C([2H])C([2H])=C43
Molecular Weight 362,5
Formulation A solution in methanol
Purity ≥99% deuterated forms (d1-d5)
Custom Code 2933.49
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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