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4-pentynoyl-Coenzyme A (trifluoroacetate salt)

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    4-<wbr/>pentynoyl-<wbr/>Coenzyme A (trifluoroacetate salt)
  • 4-<wbr/>pentynoyl-<wbr/>Coenzyme A (trifluoroacetate salt)
Cat No: 10547
Biochemicals - Labeling & Detection
Cayman

Protein acetylation is a reversible, post-translational modification regulated by lysine acetyltransferases and deacetylases and plays a key role in regulating gene expression. 4-pentynoyl-Coenzyme A (trifluoroacetate salt) (4-pentynoyl-CoA (trifluoroa...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • S-4-pentynoate coenzyme A, trifluoroacetate salt
Correlated keywords:
  • 50347-32-5 click chemistry proteins acetylation posttranslational post-translational post translational modify modification acetyl-CoA acetyl-coenzyme A lysine histons acetyl click-it click it click tag click-tag 14-pentynoyl-coa(adamantyl) indole
Product Overview:
Protein acetylation is a reversible, post-translational modification regulated by lysine acetyltransferases and deacetylases and plays a key role in regulating gene expression. 4-pentynoyl-Coenzyme A (trifluoroacetate salt) (4-pentynoyl-CoA (trifluoroacetate salt)) is an alkyne-derivatized acetyl-CoA reporter that enables rapid detection of acetylated proteins in vitro.{18193} As an acyl-CoA donor, the 4-pentynoyl analog is metabolically transferred onto lysine residues of proteins by lysine acetyltransferases. An azide-alkyne bioconjugation reaction, known as click chemistry, can then be used to readily tag acetylated proteins with fluorescent or biotinylated labels for subsequent analysis.{17991}
Size 500 µg
Shipping dry ice
Molecular Formula C26H40N7O17P3S • CF3COOH
SMILES OC(C(F)(F)F)=O.NC1=NC=NC2=C1N=CN2[C@@]3([H])[C@@](O)([H])[C@@](OP(O)(O)=O)([H])[C@](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CCC#C)=O)=O)=O)(O)=O)(O)=O)([H])O3
Molecular Weight 961,6
Formulation A lyophilized powder
Purity ≥95%
Custom Code 2915.90
UNSPSC code 12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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