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Renin (human recombinant)

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    Renin (human recombinant)
  • Renin (human recombinant)
Cat No: 10006217
Cayman
€370.00
Price is excluding VAT and does not include packaging neither shipping

Active enzyme for drug discovery research
Renin is an aspartyl protease of approximately 40 kDa produced in the kidney by juxtaglomerular cells of the macula densa. Renin converts angiotensinogen into angiotensin I, activating a major arm of renal sod...

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: 25 µg

This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • CAY-10006217
  • CAY10006217
  • CAY-10006217
Correlated keywords:
  • aspartyl
  • protease
  • kidney
  • juxtaglomerular
  • cell
  • macula
  • densa
  • angiotensinogen
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Product Overview:
Active enzyme for drug discovery research
Renin is an aspartyl protease of approximately 40 kDa produced in the kidney by juxtaglomerular cells of the macula densa. Renin converts angiotensinogen into angiotensin I, activating a major arm of renal sodium and volume auto-regulation. Native human renin is a glycoprotein derived from preprorenin by sequential cleavage of 20 and 46 amino acid residues from the N-terminus of the 406 amino acid precursor. The enzyme provided by Cayman Chemical is the mature, active, 340 amino acid protease
Size 25 µg
Shipping dry ice
Stability Store at -80 degrees; shelf life 365 days maximum after production
Formulation 50 mM Tris, pH 8.0, containing 150 mM NaCl and 5% glycerol
Purity ≥85% estimated by SDS-PAGE
Custom Code 3507907000
UNSPSC code 12352204

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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