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5-Caffeoylquinic Acid

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    5-Caffeoyl<wbr/>quinic Acid
  • 5-Caffeoyl<wbr/>quinic Acid
Cat No: 25054
Biochemicals - Ox Stress Reagents
Cayman
€86.00
Price is excluding VAT and does not include packaging neither shipping

5-Caffeoylquinic acid (5-CQA) is a phenolic compound that has been found in M. domestica and has diverse biological activities, including antioxidant, anti-inflammatory, and antidiabetic properties.{36748,36749,36750,36751} 5-CQA scavenges 2,2-dipheny...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • (1R,3R,4S,5R)-3-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid
Correlated keywords:
  • 29587-84-6 877123-86-9 5CQA Malus antiinflammatory anti-oxidant diabetic IL6 TNFα
Product Overview:
5-Caffeoylquinic acid (5-CQA) is a phenolic compound that has been found in M. domestica and has diverse biological activities, including antioxidant, anti-inflammatory, and antidiabetic properties.{36748,36749,36750,36751} 5-CQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805; EC50 = 0.184 mg/ml) and 2,2ʹ-azobis(2-amidinopropane) dihydrochloride (AAPH; Item No. 82235) radicals in cell-free assays (IC50 = 0.124 mg/ml).{36748} It decreases IL-6 and TNF-α levels in serum and macrophage infiltration into epididymal adipose tissue in rats fed a high-fat diet when administered at a dose of 90 mg/kg per day.{36750} 5-CQA (90 mg/kg per day) also decreases serum and liver free fatty acid (FFA) levels and lowers blood glucose level in an oral glucose tolerance test in high-fat diet-fed rats.{36751}
Size 5 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
CAS Number 906-33-2
Molecular Formula C16H18O9
SMILES OC1=CC=C(/C=C/C(O[C@@H]2C[C@](C(O)=O)(O)C[C@@H](O)[C@@H]2O)=O)C=C1O
Molecular Weight 354,3
Formulation A crystalline solid
Purity ≥98%
Custom Code 2907.29
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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