VE-Cadherin Anti-Cad 3 Polyclonal Antibody

Antibodies - Polyclonal Antibodies

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Cat No: A03144

Antibodies - Polyclonal Antibodies

€309.00

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Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. VE-cadherin may play a important ...

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                        Territorial Availability: Available worldwide directly through Bertin or your local distributor
                    

Synonyms:

Cadherin-5

Vascular endothelial cadherin

Correlated keywords:

VE-Cadherin

Cad3

spibio

spi-bio

A03144

Product Overview:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. VE-cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. It acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen.

Size	100 µg
Shipping	Dry ice
Host	Rabbit
Antigen	Fragment of mature VE-Cadherin
Application(s)	WB, IF
Formulation	liquid
Storage Buffer	0.1M Tris Glycine pH 7.8, 0.02% Na azide
Custom Code	3822000000
UNSPSC code	12352203

Hermant B, Bibert S, Concord E, Dublet B, Weidenhaupt M, Vernet T, Gulino-Debrac D. Identification of proteases involved in the proteolysis of vascular endothelium cadherin during neutrophil transmigration. J Biol Chem. 2003 Apr 18;278(16):14002-12.

Gulino D, Delachanal E, Concord E, Genoux Y, Morand B, Valiron MO, Sulpice E, Scaife R, Alemany M, Vernet T. Alteration of endothelial cell monolayer integrity triggers resynthesis of vascular endothelium cadherin. J Biol Chem. 1998 Nov 6;273(45):29786-93.

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