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- VE-Cadherin Anti-Cad 3 Polyclonal Antibody
VE-Cadherin Anti-Cad 3 Polyclonal Antibody
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Cat No: A03144
Antibodies
- Polyclonal Antibodies
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. VE-cadherin may play a important ...
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Territorial Availability: Available worldwide directly through Bertin or your local distributor
Synonyms:
- Cadherin-5
- Vascular endothelial cadherin
Correlated keywords:
- VE-Cadherin
- Cad3
- spibio
- spi-bio
- A03144
Product Overview:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. VE-cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. It acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen.
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. VE-cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. It acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen.
| Size | 100 µg |
| Shipping | Dry ice |
| Host | Rabbit |
| Antigen | Fragment of mature VE-Cadherin |
| Application(s) | WB, IF |
| Formulation | liquid |
| Storage Buffer | 0.1M Tris Glycine pH 7.8, 0.02% Na azide |
| Custom Code | 3822000000 |
| UNSPSC code | 12352203 |
Hermant B, Bibert S, Concord E, Dublet B, Weidenhaupt M, Vernet T, Gulino-Debrac D. Identification of proteases involved in the proteolysis of vascular endothelium cadherin during neutrophil transmigration. J Biol Chem. 2003 Apr 18;278(16):14002-12.
Gulino D, Delachanal E, Concord E, Genoux Y, Morand B, Valiron MO, Sulpice E, Scaife R, Alemany M, Vernet T. Alteration of endothelial cell monolayer integrity triggers resynthesis of vascular endothelium cadherin. J Biol Chem. 1998 Nov 6;273(45):29786-93.
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