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SN-38 Glucuronide (trifluoroacetate salt)

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    SN-38 Glucuronide (trifluoro<wbr/>acetate salt)
  • SN-38 Glucuronide (trifluoro<wbr/>acetate salt)
Cat No: 9002775
Biochemicals - Xenobiotic Metabolites
Cayman
€614.00
Price is excluding VAT and does not include packaging neither shipping

SN-38 glucuronide is an inactive metabolite of irinotecan (Item No. 14180), which is a derivative of the alkaloid camptothecin (Item No. 11694).{22661} SN-38 glucuronide is formed by glucuronidation of SN-38 (Item No. 15632), the active metabolite of ...

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: 1 mg

This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl-β-D-glucopyranosiduronic acid, trifluoroacetate salt
Correlated keywords:
  • 121080-63-5 SN38G SN38 UGT-1A1 1A7 1A10 COS7
Product Overview:
SN-38 glucuronide is an inactive metabolite of irinotecan (Item No. 14180), which is a derivative of the alkaloid camptothecin (Item No. 11694).{22661} SN-38 glucuronide is formed by glucuronidation of SN-38 (Item No. 15632), the active metabolite of irinotecan, by UDP glucuronosyl transferase 1A1 (UGT1A1) and UGT1A7. It can also be formed in COS-7 cells by UGT1A1 and UGT1A10, which are both up-regulated in an irinotecan/SN-38-resistant cell line.{38443}
Size 1 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 730 days
Molecular Formula C28H28N2O11 • XCF3COOH
SMILES O=C([C@]1(O)CC)OCC2=C1C=C(C(N=C(C=CC(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O3)=C4)C4=C5CC)=C5C6)N6C2=O.FC(F)(C(O)=O)F
Molecular Weight 568,5
Formulation A solid
Purity ≥95%
Custom Code 2932.99
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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