Confirm delete?

Bertin Bioreagent
All categories
Contact Us
You are here :

8-CPT-Cyclic AMP (sodium salt)

  • Zoom
    8-<wbr/>CPT-<wbr/>Cyclic AMP (sodium salt)
  • 8-<wbr/>CPT-<wbr/>Cyclic AMP (sodium salt)
Cat No: 12011
Biochemicals - More Biochemicals
Price is excluding VAT and does not include packaging neither shipping

A lipophilic activator of PKA and PKG (Ka = 0.05 and 0.11 ?M, respectively); inhibits PDE VA, PDE III, and PDE IV with IC50 values of 0.9, 24, and 25 ?M, respectively
8-CPT-Cyclic AMP is a lipophilic activator of the cyclic-AMP- and cyclic-GMP-dependen...


This product can only be bought through Cayman Chemical. Please contact us.

- +
Territorial Availability: Available through Bertin Technologies only in Europe
  • 8-[(4-chlorophenyl)thio]-cyclic 3',5'-(hydrogen phosphate)-adenosine, monosodium salt
  • 8-(p-Chlorophenylthio)-cAMP
  • 8-CPT-cAMP
Correlated keywords:
  • 41941-66-6
  • cyclic-AMP-dependent
  • kinases
  • cyclic-GMP-dependent
  • proteins
  • PKAs
  • PKGs
  • inhibitors
Show more...
Product Overview:
A lipophilic activator of PKA and PKG (Ka = 0.05 and 0.11 ?M, respectively); inhibits PDE VA, PDE III, and PDE IV with IC50 values of 0.9, 24, and 25 ?M, respectively
8-CPT-Cyclic AMP is a lipophilic activator of the cyclic-AMP- and cyclic-GMP-dependent protein kinases, PKA and PKG (Ka = 0.05 and 0.11 ?M, respectively). 8-CPT-cAMP inhibits cyclic GMP-specific phosphodiesterase (PDE VA), cyclic GMP-inhibited phosphodiesterase (PDE III), and cyclic AMP-specific phosphodiesterase (PDE IV) with IC50 values of 0.9, 24, and 25 ?M, respectively. It has been used in studies to analyze the signal transduction pathways initiated by cyclic-AMP- and cyclic-GMP-dependent protein kinases.
Size 10 mg
Shipping wet ice
Stability Store at -20 degrees; shelf life 730 days maximum after production
CAS Number 93882-12-3
Molecular Formula C16H14ClN5O6PS • Na
SMILES O[C@H]1[C@H](N2C(SC3=CC=C(Cl)C=C3)=NC4=C2N=CN=C4N)O[C@H]5[C@H]1OP(OC5)([O-])=O.[Na+]
Molecular Weight 493.8
Formulation A crystalline solid
Purity ≥98%
Custom Code 2903990002
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

/ We also advise you

Cross selling for this product : 8-<wbr/>CPT-<wbr/>Cyclic AMP (sodium salt) There are 10 products.