Monensin (sodium salt)

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Cat No: 16488

Monensin is a naturally occuring ionophorous antibiotic that preferentially forms complexes with monovalent cations to enable transport across lipid membranes.{26941} Through its ability to affect pH and the sodium-potassium balance of a cell, monensi...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2-[5-ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-hydroxymethyl-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-?-methoxy-?,?,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid, monosodium salt

Correlated keywords:

ionophorous antibiotics ions cations transports antimicrobials antibacterial coccicidals antivirals antimalarial infectious diseases biochemicals naturals complexes monovalent transports across lipids membranes affects affecting pH sodium-potassium sodium potassium balances cells induces deaths Gram-positives Grams positives bacteria bacterium Micrococcus Bacillus Staphylococcus M B S P falciparum Plasmodium Coccicdium C protozoa reduces reduced proliferations prevents prevented replications viruses 22136-43-2 1174161-37-5 1191082-56-0 1192220-11-3 17090-79-8 NSCs 343257 NSC-343257 NSC343257 cobans 45 coban45 coban-45 CRC Rumensin®

Product Overview:
Monensin is a naturally occuring ionophorous antibiotic that preferentially forms complexes with monovalent cations to enable transport across lipid membranes.{26941} Through its ability to affect pH and the sodium-potassium balance of a cell, monensin can induce cell death in Gram-positive bacteria such as Micrococcus, Bacillus, and Staphylococcus (MICs = 1-12.5 µg/ml), reduce proliferation of P. falciparum and Coccicdium protozoa, and also prevent replication of certain viruses.{26941}

Size	500 mg
Shipping	dry ice
CAS Number	22373-78-0
Molecular Formula	C₃₆H₆₁O₁₁ • Na
SMILES	OC[C@@]1(O)[C@H](C)C[C@H](C)[C@]([C@]2([H])O[C@]([C@]3(CC)CC[C@@]([C@@]4(C)O[C@@]5(C[C@H](O)[C@@H](C)[C@]([C@@H](C)[C@@H](OC)[C@@H](C([O-])=O)C)([H])O5)CC4)([H])O3)([H])[C@@H](C)C2)([H])O1.[Na+]
Molecular Weight	692,9
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2922.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.