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N-hexanoyl-L-Homoserine lactone

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    N-<wbr/>hexanoyl-<wbr/>L-<wbr/>Homoserine lactone
  • N-<wbr/>hexanoyl-<wbr/>L-<wbr/>Homoserine lactone
Cat No: 10007896
Biochemicals - Lipids
Cayman

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. A promising field of study involves controlling bacterial infections by quenching their quorum sensing systems. The expressi...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • N-[(3S)-tetrahydro-2-oxo-3-furanyl]-hexanamide
Correlated keywords:
  • bacterial quorums sensing signaling molecules regulatory regulates systems genes expressions cells density infections transcriptional regulators LuxIR proteins synthesis N-acylhomoserine lactones AHL cellular metabolism regulation virulence cystic fibrosis slime biofilms agriculture aquaculture food spoilage septicemia fish activation transduction signalling HHL
Product Overview:
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. A promising field of study involves controlling bacterial infections by quenching their quorum sensing systems. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-hexanoyl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, controlling gene expression, and affecting cellular metabolism.{13434} The diverse applications of this molecule include regulation of virulence in general and in cystic fibrosis, infection prevention, slime and biofilm reduction in commercial agriculture and aquaculture industries, food spoilage prevention, and septicemia in fish.{14089,14090,14091,14092,14093,14094,14095}
Size 5 mg
Shipping dry ice
CAS Number 147852-83-3
Molecular Formula C10H17NO3
SMILES CCCCCC(=O)N[C@H]1CCOC1=O
Molecular Weight 199,2
Formulation A crystalline solid
Purity ≥95%
Custom Code 2922.19
UNSPSC code 12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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