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Dihydrolipoic Acid

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    Dihydrolipoic Acid
  • Dihydrolipoic Acid
Cat No: 16372
Biochemicals - Ox Stress Reagents
Cayman
€33.00
Price is excluding VAT and does not include packaging neither shipping

Dihydrolipoic acid (DHLA) is a dithiol-containing carboxylic acid that is the reduced form of α-lipoic acid (Item No. 10005728). It acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including hydroxyl ...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe
Synonyms:
  • 6,​8-​dimercapto-octanoic acid
Correlated keywords:
  • 7516-​48-​5 119365-69-4 98441-85-1 36915-02-3 α-lipoic acids antioxidants ROSs reactive oxygens species apoptosis cells deaths dithiol-containing dithiols containing carboxylic embryonic stems cancers proliferations (±)​-​Dihydro-​α-​lipoic (±)​-​Dihydrolipoic 6,​8-​Dihydrothioctic 6,​8-​Dimercaptooctanoic 6,​8-​Dithiooctanoic DL-​Dihydro-​α-​lipoic DL-​Dihydro-​a-​lipoic DL-​Dihydro-​alpha-​lipoic DL-​Dihydro-.alpha.-​lipoic Dihydrothioctic Reduced lipoic thioctic dl-​Dihydrolipoic α-​Lipoic γ-​Lipoic
Product Overview:
Dihydrolipoic acid (DHLA) is a dithiol-containing carboxylic acid that is the reduced form of α-lipoic acid (Item No. 10005728). It acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including hydroxyl radicals, peroxynitirite, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.{26768} At concentrations of 50-100 µM, DHLA triggers apoptosis of mouse embryonic stem cells and human cancer cells, suppressing proliferation.{26767}
Size 25 mg
Shipping dry ice
Stability Store at -20 degrees; shelf life 365 days
CAS Number 462-20-4
Molecular Formula C8H16O2S2
SMILES OC(CCCCC(S)CCS)=O
Molecular Weight 208,3
Formulation A neat oil
Purity ≥95%
Custom Code 2930.90
UNSPSC code 12352100

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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