15-hydroxy Prostaglandin Dehydrogenase Substrate Screening Kit

Assay Kits - More Assay Kits

Zoom

Cat No: 701980

Assay Kits - More Assay Kits

Cayman’s 15-hydroxy Prostaglandin Dehydrogenase (15-PGDH) Substrate Screening Assay Kit provides a robust and easy-to-use platform for identifying novel substrates of the metabolic enzyme 15-PGDH. Measurement of 15-PGDH activity is carried out by moni...

This product can only be bought through Cayman Chemical. Please contact us.

Product Overview
Data
Downloads
About Cayman

Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

15PGDH PGE 2

Product Overview:
Cayman’s 15-hydroxy Prostaglandin Dehydrogenase (15-PGDH) Substrate Screening Assay Kit provides a robust and easy-to-use platform for identifying novel substrates of the metabolic enzyme 15-PGDH. Measurement of 15-PGDH activity is carried out by monitoring the rate of NAD+ reduction to NADH. The reduction of NAD+ to NADH is accompanied by an increase in fluorescence at 445 nm following excitation at 340 nm. Prostaglandin E2 (PGE2) is included as a positive control while 15-keto PGE2, an inactive metabolite of PGE2 formed by 15-PGDH, is included as a negative (background) control. This assay is also able to detect “slow” substrates, which are utilized by 15-PGDH less efficiently than PGE2.

Size	96 wells
Shipping	dry ice
Custom Code	3822.19
UNSPSC code	41116104

Technical File

MSDS

Click here to ask for your quote and get 15% off Cayman's products.

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

All products

My account

Connect or create an account

Supplier

Product Type

Application