Glufosinate-d3 (hydrochloride)

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Glufosinate-d₃ (hydrochloride)

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Cat No: 34447

Biochemicals - Isotopically Labeled Standards

Glufosinate-d3 is intended for use as an internal standard for the quantification of glufosinate (Item No. 16675) by GC- or LC-MS. Glufosinate is a broad-spectrum herbicide and racemic mixture of L-phosphinothricin, a phytotoxic compound, and D-phosph...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2-amino-4-(hydroxy(methyl-d3)phosphoryl)butanoic acid, monohydrochloride

Correlated keywords:

1323486-77-6 deuterated deuterium GCMS LCMS GS-1 2 Elodea Lolium HOE 00661 39866 HOE00661 HOE39866

Product Overview:
Glufosinate-d3 is intended for use as an internal standard for the quantification of glufosinate (Item No. 16675) by GC- or LC-MS. Glufosinate is a broad-spectrum herbicide and racemic mixture of L-phosphinothricin, a phytotoxic compound, and D-phosphinothricin, its inactive enantiomer.{60605} It is an irreversible inhibitor of glufosinate synthetase 1 (GS1) and GS2 (Kis = 1.1. and 4.8 µM, respectively), enzymes that are required for nitrogen metabolism in plants. Glufosinate induces the production of reactive oxygen species (ROS) and lipid peroxidation in plant cell membranes. It reduces dry biomass of the weeds E. canadensis and L. rigidum with ED50 values of 26 and 763 g/hectare, respectively. Glufosinate has no observed adverse effects in rats and mice when administered at doses of 4.1 and 17 mg/kg per day for three months. Formulations containing glufosinate have been used as foliar herbicides in agriculture.

Size	1 mg
Shipping	dry ice
CAS Number	1323254-05-2
Molecular Formula	C₅H₉D₃NO₄P • HCl
SMILES	OC(C(N)CCP(C([2H])([2H])[2H])(O)=O)=O.Cl
Molecular Weight	220,6
Formulation	A solid
Purity	≥99% deuterated forms (d1-d3)
Custom Code	3822.19
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.