Dinotefuran

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Dinotefuran

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Cat No: 33802

Biochemicals - Pesticides

Dinotefuran is a neonicotinoid insecticide.{61398} It is an agonist of nicotinic acetylcholine receptors (nAChRs), inducing inward currents in isolated American cockroach (P. americana) neurons with an EC50 value of 7.6 µM. Dinotefuran, alone or in co...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

N??-methyl-N-nitro-N?-[(tetrahydro-3-furanyl)methyl]-guanidine

Correlated keywords:

222540-72-9 Alpine WSG Arubarin Mikeblock MTI446 Safari Starkle Tenchu Venom Zylam Periplaneta Anopheles Culex Aedes

Product Overview:
Dinotefuran is a neonicotinoid insecticide.{61398} It is an agonist of nicotinic acetylcholine receptors (nAChRs), inducing inward currents in isolated American cockroach (P. americana) neurons with an EC50 value of 7.6 µM. Dinotefuran, alone or in combination with the metabolic inhibitors piperonyl butoxide (PB; Item No. 25820) or propargyl propyl benzenephosphonate (NIA), induces mortality in adult P. americana.{61399} It is lethal to insecticide-sensitive or -resistant strains of A. gambiae, C. quinquefasciatus, and A. aegypti in larval (LC50s = 0.14-0.44 mg/L) and adult (LD50s = 0.18-31.16 ng/mg) bioassays.{61400} Dinotefuran has been found in a variety of commercial foodstuffs, including rice, cucumber, milk, egg, and pork samples, as well as in water samples from freshwater streams.{61401,61402} Formulations containing dinotefuran have been used in the agricultural and veterinary control of insect infestations.

Size	50 mg
Shipping	dry ice
CAS Number	165252-70-0
Molecular Formula	C₇H₁₄N₄O₃
SMILES	CN/C(N[N+]([O-])=O)=N\CC1CCOC1
Molecular Weight	202,2
Formulation	A solid
Purity	≥98%
Custom Code	2932.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.