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JWH 424

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    JWH 424
  • JWH 424
Cat No: 9001203
Cayman
€74.00
Price is excluding VAT and does not include packaging neither shipping

An 8-bromonaphthyl derivative of JWH 018 which shows a reduced selectivity for CB1 over CB2 (Ki = 20.9 and 5.4, respectively); intended for forensic and research applications
JWH 018 is a synthetic cannabinoid (CB) that potently activates the central C...

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This product can only be bought through Cayman Chemical. Please contact us.

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Territorial Availability: Available through Bertin Technologies only in Europe. This product is intended for forensic and research applications.
Technical Warning: Bertin Technologies restricts the sale of this product to licensed controlled substances laboratories and qualified academic research institutions. Please consult our General Terms and conditions of Sales for further details.
Synonyms:
  • (8-bromonaphthalen-1-yl)(1-pentyl-1H-indol-3-yl)methanone
Correlated keywords:
  • cannabinoids
  • CBs
  • cannabimimetics
  • CB1
  • CB2
  • receptors
  • agonists
  • spices
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Product Overview:
An 8-bromonaphthyl derivative of JWH 018 which shows a reduced selectivity for CB1 over CB2 (Ki = 20.9 and 5.4, respectively); intended for forensic and research applications
JWH 018 is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. JWH 424 is an 8-bromonaphthyl derivative of JWH 018 which shows a reduced selectivity for CB1 over CB2 (Ki = 20.9 and 5.4 nM, respectively). The properties of this compound in vivo are not known. This product is intended for forensic and research applications.
Size 5 mg
Shipping wet ice
Stability Store at -20 degrees; shelf life 365 days maximum after production
CAS Number 1366068-04-3
Molecular Formula C24H22BrNO
SMILES O=C(C1=CN(CCCCC)C2=C1C=CC=C2)C3=C4C(C=CC=C4Br)=CC=C3
Molecular Weight 420.3
Formulation A solution in methanol
Purity ≥98%
Custom Code 2903990002
UNSPSC code 12352100
UN Number UN1230

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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