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  • Reserpine
Cat No: 16474
Biochemicals - Natural Products

Reserpine is an alkaloid isolated from dried roots of R. serpentine, which is used in traditional Indian medicine. Reserpine irreversibly inhibits both human isoforms of vesicular monoamine transporter, VMAT1 and VMAT2 (Kis = 34 and 12 nM, respectivel...


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Territorial Availability: Available through Bertin Technologies only in France
  • (3?,16?,17?,18?,20?)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester
Correlated keywords:
  • 1407-?38-?1 8048-?25-?7 141099-?49-?2 873409-?80-?4 natural products inhibitors neuroscience apoplon NSC 237659 NSC 59272 serpalan serpasil serpentine alkaloids inhibits VMATs VMAT-1 VMAT-2 vesicular monoamines p-glycoproteins hiserpia Rauwolfia serpentine anquil apoplon banasil bioserpine carpacil crystoserpine deserpine ENT 50146 elserpine eserpine eskaserp hiposerpil kitine lemiserp loweserp mayserpine quiescin rau-?sed raucap raulen raunervil raupasil raurine rausedyl rausingle rauwasedin resercaps resercen reserlor reserpamed reserpex reserpil reserpoid resine respital restran riserpa rivasin roxinoid sandril sedaraupin sedserp serfin serolfia serp-?AFD serpaloid serpanray serpasil serpasil serpasol serpasil premix serpasol serpate serpen serpentina serpicon serpiloid serpines serpine serpipur sertabs sertina T-?serp temposerpine triserpin vio-?serpine
Product Overview:
Reserpine is an alkaloid isolated from dried roots of R. serpentine, which is used in traditional Indian medicine. Reserpine irreversibly inhibits both human isoforms of vesicular monoamine transporter, VMAT1 and VMAT2 (Kis = 34 and 12 nM, respectively).{26972,26973} As this leads to metabolism of monoamines, reserpine is used to experimentally deplete monoamines in animals.{26970,26971,20200} Reserpine also inhibits the multidrug resistance protein P-glycoprotein (IC50 = 0.5 µM).{25345}
Size 1 g
Shipping dry ice
CAS Number 50-55-5
Molecular Formula C33H40N2O9
SMILES COC1=CC(C(O[C@@H]2C[C@@](CN(CCC3=C4NC5=C3C=CC(OC)=C5)[C@]4([H])C6)([H])[C@@]6([H])[C@H](C(OC)=O)[C@H]2OC)=O)=CC(OC)=C1OC
Molecular Weight 608,7
Formulation A crystalline solid
Purity ≥98%
Custom Code 2939.79
UNSPSC code 12352100

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