Palmitoyl Ethanolamide-d4

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Palmitoyl Ethanolamide-d₄

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Cat No: 10007824

Biochemicals - Isotopically Labeled Standards

Palmitoyl ethanolamide-d4 (PEA-d4) contains four deuterium atoms at the 7, 7', 8, and 8' positions. It is intended for use as an internal standard for the quantification of PEA by GC- or LC-mass spectrometry. PEA is an endogenous cannabinoid found in ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

N-(2-hydroxyethyl)-hexadecanamide-7,7,8,8-d4

Correlated keywords:

GC/MS deuteriums isotopes internal standards deuterateds LC/MS GC-MS LC-MS mass spectrometry neurochemistry neuroscience endocannabinoids CB2 neurotransmitters receptors ligands PEA N-(2-hydroxyethyl)-hexadecanamide cyclic cAMP ethanolamides anandamides AEA fatty acids neurochemistry ethanolamines cannabinoids cbs synthetic

Product Overview:
Palmitoyl ethanolamide-d4 (PEA-d4) contains four deuterium atoms at the 7, 7', 8, and 8' positions. It is intended for use as an internal standard for the quantification of PEA by GC- or LC-mass spectrometry. PEA is an endogenous cannabinoid found in brain, liver, and other mammalian tissues.{2415} PEA has also been isolated from egg yolk, and found to have anti-anaphylactic and anti-inflammatory activity in vitro.{1633} PEA is an endocannabinoid which has been shown to significantly elevate cyclic AMP in cells expressing peripheral cannabinoid (CB2) receptors. However, its affinity for CB2 receptors is relatively low, at about 10 µM. Central cannabinoid (CB1) receptors have no appreciable affinity for PEA.{1134}

Size	100 µg
Shipping	dry ice
CAS Number	1159908-45-8
Molecular Formula	C₁₈H₃₃D₄NO₂
SMILES	OCCN([H])C(CCCCCC([2H])([2H])C([2H])([2H])CCCCCCCC)=O
Molecular Weight	303,5
Formulation	A solution in ethanol
Purity	≥99% deuterated forms (d1-d4)
Custom Code	3822.19
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.