p53 Product Pack

Biochemicals - Small Molecule Activators

Cat No: 10005291

Biochemicals - Small Molecule Activators

The Cayman p53 Product Pack contains PRIMA-1, a p53 re-activator that restores the apoptotic activity of mutant p53 via conformational modulation.{9837} Included in the p53-PAK is Cayman’s p53 (Phospho-Ser392) Polyclonal Antibody (Item No. 10004807), ...

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Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

DNA binding anti-oncogenic apoptosis cancer p53 re-activators reactivators induces apoptotic re-activation reactivation antioncogenic packs

Product Overview:
The Cayman p53 Product Pack contains PRIMA-1, a p53 re-activator that restores the apoptotic activity of mutant p53 via conformational modulation.{9837} Included in the p53-PAK is Cayman’s p53 (Phospho-Ser392) Polyclonal Antibody (Item No. 10004807), as well as (±)-Nutlin-3 (Item No. 10004372), a p53 activator working via inhibition of p53/Mdm2 binding.{11628} Cayman’s Caylin-2 (Item No. 10005002), a nutlin analog with growth enhancing properties at low concentrations that are opposite those of (±)-nutlin-3.{11983}

Size	1 ea
Shipping	dry ice
Custom Code	3822.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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