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EC 23

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    EC 23
  • EC 23
Cat No: 9002073
Biochemicals - More Biochemicals
Cayman

All-trans retinoic acid (ATRA, Item No. 11017) is frequently used in cell culture to induce stem cell differentiation or enhance the growth, differentiation, and maintenance of neural cell types.{27145,27146,27147} Unfortunately, ATRA is readily susce...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl]-benzoic acid
Correlated keywords:
  • ATRA retinoid photostable synthetic analog differentiation pluripotent embryonic stem cells research All-trans retinoic acid cell culture intracellular signaling nuclear receptors biochemical AGN 190205 BASF 46928 AGN190205BASF46928
Product Overview:
All-trans retinoic acid (ATRA, Item No. 11017) is frequently used in cell culture to induce stem cell differentiation or enhance the growth, differentiation, and maintenance of neural cell types.{27145,27146,27147} Unfortunately, ATRA is readily susceptible to isomerisation and degradation upon exposure to light or other factors such as temperature and oxidation, which presents confounding issues for cell culture. EC 23 is a photostable synthetic analog of ATRA that induces differentiation in human pluripotent embryonic stem cells when used within the range of 100 nM-10 µM.{27145,27146,27147}
Size 1 mg
Shipping dry ice
CAS Number 104561-41-3
Molecular Formula C23H24O2
SMILES CC1(C)C2=C(C=CC(C#CC3=CC=C(C(O)=O)C=C3)=C2)C(C)(C)CC1
Molecular Weight 332,4
Formulation A crystalline solid
Purity ≥98%
Custom Code 2916.39
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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Cross selling for this product : EC 23 There is one product.

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