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ML-336

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    ML-<wbr/>336
  • ML-<wbr/>336
Cat No: 9001920
Biochemicals - Anti-Infection
Cayman

Venezuelan Equine Encephalitis Virus (VEEV) is a mosquito-borne alphavirus that can cause encephalomyelitis in all equine species and also in humans. ML-336 is a quinazolinone-based compound that has been shown to inhibit a VEEV-induced cytopathic effe...

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Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • 2-[(E)-(1,4-dimethyl-2-piperazinylidene)amino]-5-nitro-N-phenyl-benzamide
Correlated keywords:
  • molecular library initiatives CIDs 71301451 SIDs 144087340 encephalomyelitis Venezuelan Equine Encephalitis Virus VEEV alphavirus infectious diseases antiviral non-structural proteins viral RNA replications nsP2 anti virals Venezuelan equine encephalitis virus MLs 336 ML336 anti-viral quinazolinone quinazolinone-based inhibits inhibitors inhibitions
Product Overview:
Venezuelan Equine Encephalitis Virus (VEEV) is a mosquito-borne alphavirus that can cause encephalomyelitis in all equine species and also in humans. ML-336 is a quinazolinone-based compound that has been shown to inhibit a VEEV-induced cytopathic effect in three strains of the virus (IC50s = 32, 20, and 41 nM for TC-83, V3526, and Trinidad donkey strains, respectively).{26236} It is reported to target the VEEV non-structural protein 2, which is necessary for transcription and replication of viral RNA.{26236}
Size 1 mg
Shipping dry ice
CAS Number 1613465-33-0
Molecular Formula C19H21N5O3
SMILES CN1CCN(C)C/C1=N\C2=C(C(NC3=CC=CC=C3)=O)C=C([N+]([O-])=O)C=C2
Molecular Weight 367,4
Formulation A crystalline solid
Purity ≥95%
Custom Code 2933.59
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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