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CEP-Lysine-d4

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    CEP-<wbr/>Lysine-<wbr/>d<sub>4</sub>
  • CEP-<wbr/>Lysine-<wbr/>d<sub>4</sub>
Cat No: 9000595
Biochemicals - Isotopically Labeled Standards
Cayman

CEP-Lysine-d4 contains four deuterium atoms at the carboxyethyl 2,3',3,3' positions. It is intended for use as an internal standard for the quantification of CEP-lysine by GC- or LC-mass spectrometry (MS). Docosahexaenoic acid (DHA) is an ω-3 polyunsa...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • (S)-2-amino-6-(2-(2-carboxy-ethyl)-1H-pyrrol-1-yl)-hexanoic-2,2',3,3'-d4-acid
Correlated keywords:
  • Docosahexaenoic acid DHA oxidative stress 2-(?-carboxyethyl)pyrrole CEP carboxyethylpyrrole advanced glycation end products biomarkers age-related macular degeneration deuterateds internal standard GC LC chromatography mass spectrometry GC-MS LC-MS GC/MS LC/MS deuterium
Product Overview:
CEP-Lysine-d4 contains four deuterium atoms at the carboxyethyl 2,3',3,3' positions. It is intended for use as an internal standard for the quantification of CEP-lysine by GC- or LC-mass spectrometry (MS). Docosahexaenoic acid (DHA) is an ω-3 polyunsaturated fatty acid that is abundant in the brain and in photoreceptor cell membranes in the retina. Oxidative cleavage of phospholipids containing DHA produces reactive electophilic phospholipid fragments, including 4-hydroxy-7-oxohept-5-enoates.{18414} These can interact with the primary amine group of lysyl residues to produce 2-(ω-carboxyethyl)pyrrole (CEP) derivatives, which are abundant in certain diseases.{18412,18416} Advanced glycation end products, including CEP-lysine are biomarkers for age-related macular degeneration.{18413,18415} CEP-lysine-d4 is a deuterated form of CEP-lysine.
Size 500 µg
Shipping dry ice
Molecular Formula C13H16D4N2O4
SMILES OC(C([2H])([2H])C([2H])([2H])C1=CC=CN1CCCC[C@H](N)C(O)=O)=O
Molecular Weight 272,3
Formulation A crystalline solid
Purity ≥99% deuterated forms (d1-d4)
Custom Code 3822.19
UNSPSC code 12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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