Pregnanediol-3-Glucuronide (PDG)

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Pregnanediol-3-Glucuronide (PDG) ELISA Kit

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Cat No: 501300

Assay Kits - Elisa

Pregnanediol-3-Glucuronide (5β-pregnane-3α,20α-diol-3α-glucuronide, PDG or P3G) is the major metabolite of progesterone, an endogenous steroid and the most important member of the class of steroid hormones known as progestogens. Progesterone is import...

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Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

neurosteroid

Product Overview:
Pregnanediol-3-Glucuronide (5β-pregnane-3α,20α-diol-3α-glucuronide, PDG or P3G) is the major metabolite of progesterone, an endogenous steroid and the most important member of the class of steroid hormones known as progestogens. Progesterone is important in a variety of biological functions such as preparing the endometrium for implantation, maintaining pregnancy, differentiating breast tissue, and promoting normal development of neurons in the brain as a neuro steroid. Low progesterone levels are linked to chronic anovulation which is reported to be associated with female infertility, breast cancer and endometrial cancer.{35256,35090} Levels of PDG in the urine correlate highly to levels of progesterone measured in the serum.{40241,1594} PDG analysis may be used as a non-invasive method to indirectly measure progesterone and therefore might be used as a biomarker for luteal activity, ovarian cancer, and a variety of other biological disorders.{35257,35088,35258}

Size	96 solid wells
Shipping	dry ice
Custom Code	3822.19
UNSPSC code	41116104

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.