tetranor-PGDM ELISA Kit

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Cat No: 501001

Assay Kits - Elisa

tetranor-PGDM is a major metabolite of prostaglandin D2 (PGD2) found in human and mouse urine.{15162} In human urine, tetranor-PGDM is significantly more abundant than the PGD2 metabolites 11β-PGF2α and 2,3-dinor-11β-PGF2α and is the only endogenous P...

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Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

immunosorbents ELISAs solid strip plates prostaglandins PGs metabolites acetylcholinesterases tracers enzymes immunoassays ELISAs EIAs kits measures measurements hemoatopoietic-types lipocalin-types H-PGDS L-PGDS synthases isoforms PGD2 D2 allergen-stimulated mast cells pro-inflammatory mediators allergic reactions 7-transmembranes G protein-coupled receptors GPCRs human mouse murine LC-MS liquid chromatography mass-spectrometry creatinine competitive quantifications assays PGD-M urine catalyzes isomerizations sleep nociception inhibits inhibitors inibition platelets aggregations enzymes central nervous systems male genitals organs mammals hearts b-trace beta-trace .beta.-trace ?-trace cerebrospinal fluids peripheral tissues antigen-presenting cells mast megakaryocytes allergen-stimulating proinflammatory pro-inflammatory transduced transductions DP1 CRTH2/DP2

Product Overview:
tetranor-PGDM is a major metabolite of prostaglandin D2 (PGD2) found in human and mouse urine.{15162} In human urine, tetranor-PGDM is significantly more abundant than the PGD2 metabolites 11β-PGF2α and 2,3-dinor-11β-PGF2α and is the only endogenous PGD2 metabolite detectable in mouse urine by LC-MS. Normal levels of tetranor-PGDM in human and mouse urine are 1.5 ng/mg creatinine and 8.1 ng/mg creatinine respectively.{15162} Cayman’s tetranor-PGDM ELISA Kit is a competitive assay that can be used for quantification of tetranor-PGDM in urine. This assay converts tetranor-PGDM to a stable derivative, tetranor-PGJM, that can be easily quantified. The assay has a range from 6.4-4,000 pg/ml and a sensitivity (80% B/B0) of approximately 40 pg/ml.

Size	96 solid wells
Shipping	dry ice
Custom Code	3822.19
UNSPSC code	41116104

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.