2-chloro-N6-Cyclopentyladenosine

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2-chloro-N⁶-Cyclopentyladenosine (hydrate)

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Cat No: 28731

Biochemicals - Receptor Pharmacology

2-chloro-N6-Cyclopentyladenosine is an adenosine receptor agonist.{52004} It binds selectively to adenosine A1 receptors over A2A and A3 receptors with Ki values of 0.83, 2,300 and 42 nM, respectively, for the human recombinant receptors expressed in ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2-chloro-N-cyclopentyl-adenosine, hemihydrate

Correlated keywords:

172613-66-0 37739-05-2 CC PA A 1 2A 3

Product Overview:
2-chloro-N6-Cyclopentyladenosine is an adenosine receptor agonist.{52004} It binds selectively to adenosine A1 receptors over A2A and A3 receptors with Ki values of 0.83, 2,300 and 42 nM, respectively, for the human recombinant receptors expressed in CHO cells. 2-chloro-N6-Cyclopentyladenosine decreases heart rate in isolated rat atria (EC50 = 8.2 nM) but does not affect vasodilation in bovine coronary arteries.{52005} It inhibits convulsions induced by isoniazid (Item No. 20378) and pentylenetetrazole (Item No. 18682) in mice when administered at a dose of 8.3 μmol/kg.{52006}

Size	5 mg
Shipping	dry ice
Molecular Formula	C₁₅H₂₀ClN₅O₄ • 0.5H₂O
SMILES	OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C(NC4CCCC4)N=C(Cl)N=C32)O1
Molecular Weight	378,8
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2934.99
UNSPSC code	12352100

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2-chloro-N6-Cyclopentyladenosine (hydrate)