Methylisothiazolinone

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Cat No: 28136

Biochemicals - Kinase Inhibitors

Methylisothiazolinone (MI) is an isothiazolinone-derived biocide used for controlling microbial growth in industrial and household products, often in a mixture with 5-chloro-2-methyl-3-isothiazolone (MCI).{37117,30031} MI is active against Gram-positi...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2-methyl-3(2H)-isothiazolone

Correlated keywords:

125794-71-0 184720-17-0 1610617-47-4 MIT 950 MIT950 MIT10 Acticide M 10 20M10 M20 Bestcide 600 Kathon CG 243 Kordek 50C 573F LX 5000 LX5000 MLX 10 MT10 Microcare Neolone CapG PE M50 Optiphen ProClin proclin5000 SPX Zonen-MT zonenmt Staphylococcus Pseudomonas Aspergillus Candida KB 838 KB838 22589

Product Overview:
Methylisothiazolinone (MI) is an isothiazolinone-derived biocide used for controlling microbial growth in industrial and household products, often in a mixture with 5-chloro-2-methyl-3-isothiazolone (MCI).{37117,30031} MI is active against Gram-positive and Gram-negative bacteria, fungi, and yeast with MIC values of 0.0045, 0.0015, >0.01, and 0.0065% (w/w) for S. aureus, P. aeruginosa, A. niger, and C. albicans, respectively, when used alone.{37117} MIC values are 7 to 200-fold lower when MI is used in combination with MCI. MI decreases neurite outgrowth of rat cortical neurons when used at concentrations of 0.1-3 µM and inhibits Src family kinases in cell-free assays.{37116} MI, alone and as a mixture with MCI, can elicit contact sensitization.{30031}

Size	1 mL
Shipping	dry ice
CAS Number	2682-20-4
Molecular Formula	C₄H₅NOS
SMILES	CN1SC=CC1=O
Molecular Weight	115,2
Formulation	A 50% (w/v) aqueous solution
Purity	≥98%
Custom Code	2930.90
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.