Azacyclonol

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Azacyclonol

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Cat No: 27303

Biochemicals - More Biochemicals

Azacyclonol is a CNS depressant.{43955} It reduces transmission through the sympathetic ganglia, decreasing electrically stimulated contractile responses in feline nictitating membrane. It reduces coordinated locomotor activity in mice by greater than...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

?,?-diphenyl-4-piperidinemethanol

Correlated keywords:

595598-07-5 MDL4829 MER17 Frenoton Psychosan 3A4 450 Ataractan Calmeran

Product Overview:
Azacyclonol is a CNS depressant.{43955} It reduces transmission through the sympathetic ganglia, decreasing electrically stimulated contractile responses in feline nictitating membrane. It reduces coordinated locomotor activity in mice by greater than 50% when administered at doses of 71, 142, and 213 mg/kg.{43952} Azacyclonol (142 mg/kg) decreases hyperactivity induced by pipradol, D-amphetamine, morphine, and cocaine. It also increases the duration of sleeping time induced by hexobarbital. Azacyclonol is also a metabolite of the histamine H1 receptor antagonist terfenadine (Item No. 20305).{43953,43954} It is formed from terfenadine by the cytochrome P450 (CYP) isoform CYP3A4.{43954}

Size	10 g
Shipping	dry ice
CAS Number	115-46-8
Molecular Formula	C₁₈H₂₁NO
SMILES	OC(C1=CC=CC=C1)(C2=CC=CC=C2)C3CCNCC3
Molecular Weight	267,4
Formulation	A solid
Purity	≥95%
Custom Code	2933.39
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.